Investigation of Resistance to the Antibiotic Penicillin, Cefteriaxone, Ciprofloxacin and Cefixime in Neisseria Gonorrhoeae Sampled from Patients Infected with the Gonorrhea in Poona City, India

Background and Objectives: In the recent decade, resistance of neisseria gonorrhea has increased as a result of vast and improper consumption of antibiotics. Moreover lack of information about the last patterns of antibiotic resistance and the way of development and transmission of this resistance is a great challenge to treatments of infections from these bacteria. This study was performed in order to investigate antibiotic resistance and penicillinase production in gonococcal strains sampled from patients with gonorrhea in poona, a big city in India. 160 patients suspected to gonorrhea infection were studied. Materials and Methods: In this study in 2014, diagnosis performed by history, physical examination, Gram stain and culture on the medium tire Martin. Results: 40 patients (25%) were culture positive and the resistances to such antibiotics were tested: penicillin: 81.4%, ciprofloxacin: 74.2%, ceftriaxone: 0.8% Investigation of resistance to the antibiotic penicillin... and cefixime: 9%. strains resistant to penicillin, were penicillinase-producing enzymes. Conclusion: Among cephalosporins, ciprofloxacin and penicillin are not proper choises and cefixime and ceftriaxone are the only antibiotics to choose for treatment of gonorrhea.